The Division of Human Anatomy and Structural Biology
Duke Tanaka, Jr., Ph.D.
University of Chicago; Professor
The overall objective of our research is to delineate the effects of specific
neurotoxicants on the neuroanatomy of the central nervous system. Our work
has been centered around several topics including assessing the effects of
exposure to organophosphorus compounds and polychlorinated biphenyls (PCBs)
on the mature and developing avian and mammalian central nervous system, determining
the effects of exposure to Great Lakes toxicants on the developing central
nervous system, and studying the effects of administration of phenylmethylsulfonyl
fluoride on the severity of organophosphorus-induced delayed neurotoxicity
in developing chicks. Techniques employed include silver degeneration stains,
immunocytochemistry, and quantitative imaging.
